Prof. Carmit Levy
Research work
My lab aim to identify melanoma progression drivers independent of mutation acquisition and the effect of UV exposure on the skin and human physiology. Currently we are interested in mechanism of prevention and treatment of melanoma brain metastases.
Areas of interest & scientific knowledge
Brain Disorders Research
Cellular & Molecular Neuroscience
Selected Publications
- Golan, T., Messer, A.M., Amitai-Lange, A., Melamed, Z., Bell, R.E., Ohana, R., Kapitansky, O., Lerman, G., Greenberger, S., Khaled, M., Amar, N., Albrengues, J., Gaggioli, C., Gonen, P., Tabach, Y., Sprinzak, D., Shalom-Feuerstein, R., and Levy, C. (2015). Interactions of melanoma cells with distal keratinocytes trigger metastasis via Notch signaling inhibition of MITF. Molecular Cell. doi: 10.1016/j.molcel.2015.06.028.
- Dror, S., Laureen Sander, L., Schwartz, H., Sheinboim, D., Barzilai, A., Dishon, Y., Apcher, S., Golan, T., Greenberger, S., Barshack, I., Malcov, H., Zilberberg, A., Nessling, M., Friedmann, Y., Igras, V., Barzilay, O., Vaknine, H., Brenner, R., Zinger, A., Schroeder, A., Gonen, P., Khaled, M., Erez, N., Hoheisel, J. D. and Levy, C. (2016). Melanoma miRNA trafficking controls tumor niche formation. Nature Cell Biology. doi: 10.1038/ncb3399
- Sheinboim, D., Maza, I., Dror, I., Parikh, S., Krupalnik, V., Bell, R. E., Zviran, A., Suita, Y., Hakim, O., Mandel-Gutfreund, Y., Khaled, M., Hanna, J. H., and Levy, C. (2017). OCT4 impedes cell fate redirection by the melanocyte lineage master regulator MITF in mouse ESCs. Nature Communications. doi: 10.1038/s41467-017-01122-1
- Malcov-Brog, H., Alpert, A., Golan, T., Parikh, S., Nordlinger, A., Netti, F., Sheinboim, D., Dror, I., Thomas, L., Cosson, C., Gonen, P., Stanevsky, Y., Brenner, R., Perluk, T., Frand, J., Elgavish, S., Nevo, Y., Rahat, D., Tabach, Y., Khaled, M., Shen-Orr, S. S., and Levy, C. (2018). UV-Protection Timer Controls Linkage between Stress and Pigmentation Skin Protection Systems. Molecular Cell. doi: 10.1016/j.molcel.2018.09.022
- Parikh S, Parikh R, Michael K, Bikovski L, Barnabas G, Mardamshina M, Hemi R, Manich P, Goldstein N, Malcov H, Ben-Dov T, Glaich O, Liber D, Bornstein Y, Khaled M, Ziv T, Pavlovsky M, Brenner R, Percik R, Perluk T, Karnieli-Miller O, Ben-Eliyahu S, Barak S, Gepner Y, Weiss R, Pfluger P, Weller A, Levy C. (2022). Solar exposed skin induces sex dependent food seeking behavior. Nature Metabolism. 2022 In press
