Prof. Uri Ashery

Prof. Uri Ashery

Brain Disorders Research

Research work

Learning and memory in health and disease. Our team focuses on elucidating the molecular mechanisms of learning and memory, and their link to neurodegenerative diseases.

Our lab combines multidisciplinary approaches such as electrophysiology, Multi electrode array, super-resolution microscopy (dSTORM and STED), Molecular biology, animal behavior study and computer modeling to study synaptic plasticity and correlate between molecular changes and synaptic function and dysfunction. Our main focus currently is on the following directions:

 

  • Investigating synaptic plasticity processes at the hippocampal mossy fiber synapses and understanding the mechanisms of cAMP dependent synaptic plasticity.
  • Elucidating the mitigating effects of hyperbaric oxygen treatment (HBOT) in Alzheimer's disease (AD) mouse models.
  • Identifying early biomarkers for Parkinson’s disease (PD) and Investigating the effect of alpha-synuclein aggregation on neuronal activity.
Areas of interest & scientific knowledge

Brain Disorders Research

  • Alzheimer’s diseases
  • Animal Studies
  • Autism
  • Electrophysiology
  • Microscopy
  • Neurodegenerative diseases
  • Neurodevelopmental disorders
  • Parkinson’s disease

System & Physiological Neuroscience

  • Animal Behavior
  • Biophysics
  • Circuits and networks
  • Computational modeling
  • Electrophysiology
  • Neurodegenerative diseases
  • Plasticity

Cellular & Molecular Neuroscience

  • Animal Studies
  • Biophysics
  • Cell biology
  • Cell culture
  • Circuits and networks
  • Computational modeling
  • Electrophysiology
  • iPSC
  • Microscopy
  • Molecular biology
  • Neurobiology
  • Plasticity
  • stem cell
Selected Publications
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