Prof. Tamir Tuller
Research work
In my lab, we developed AI and computational models to understand, predict, and engineer all gene expression steps (e.g. transcription, translation, splicing, co-translational folding). We use our models for understanding the way genetics affect cancer and neurological diseases. In addition, based on our models we develop innovative therapies for cancer and neurological diseases (e.g. RNA based therapies).
Areas of interest & scientific knowledge
Cellular & Molecular Neuroscience
Neurodevelopment and Neurogenetic Research
Computational & Theoretical Neuroscience
Selected Publications
- Tamir Tuller, Shimshi Atar, Eytan Ruppin, Michael Gurevich, and Anat Achiron. Global map of physical interactions among differentially expressed genes in multiple sclerosis relapses and remissions. Hum Mol Genet. 2011 Sep 15;20(18):3606-19. http://www.cs.tau.ac.il/~tamirtul/Selected_publications/HMG2011.pdf
- Tuller T, Atar S, Ruppin E, Gurevich M, Achiron A. Common and specific signatures of gene expression and protein-protein interactions in autoimmune diseases.
Genes Immun. 2013 Mar;14(2):67-82. https://www.nature.com/articles/gene201255 - A. Diament, I. Weiner, N. Shahar, S. Landman, Y. Feldman, S. Atar, M. Avitan, S. Schweitzer, I. Yacoby, T. Tuller. ChimeraUGEM: unsupervised gene expression modeling in any given organism. Bioinformatics. 2019. http://www.cs.tau.ac.il/~tamirtul/Selected_publications/Bioinformatics2019.pdf
