Prof. Pablo Blinder
Research work
The PBLab is a multidisciplinary environment focused on the study of neurovascular coupling and the structure of the neurovascular unit. The laboratory implements and develops cutting-edge imaging tools based on multi-photon microscopy geared to obtain fast neuronal and vascular dynamics. In addition, the laboratory studies different pathologies involving brain vasculature, such as hypertension and cortical microinfarcts.
Areas of interest & scientific knowledge
Imaging Research
System & Physiological Neuroscience
Specialization
Selected Publications
- Cerebrospinal fluid influx drives acute ischemic tissue swelling. Mestre H, Du T, Sweeney AM, Liu G, Samson AJ, Peng W, Mortensen KN, Stæger FF, Bork PAR, Bashford L, Toro ER, Tithof J, Kelley DH, Thomas JH, Hjorth PG, Martens EA, Mehta RI, Solis O, Blinder P, Kleinfeld D, Hirase H, Mori Y, Nedergaard M. Science. 2020 Mar 13;367(6483):eaax7171. doi: 10.1126/science.aax7171. Epub 2020 Jan 30. PMID: 32001524
- Prophylactic TLR9 stimulation reduces brain metastasis through microglia activation. Benbenishty A, Gadrich M, Cottarelli A, Lubart A, Kain D, Amer M, Shaashua L, Glasner A, Erez N, Agalliu D, Mayo L, Ben-Eliyahu S, Blinder P. PLoS Biol. 2019 Mar 28;17(3):e2006859. doi: 10.1371/journal.pbio.2006859. eCollection 2019 Mar. PMID: 30921319
- Hagai Har-Gil, Lior Golgher, Shai Israel, David Kain, Ori Cheshnovsky, Moshe Parnas, and Pablo Blinder, "PySight: plug and play photon counting for fast continuous volumetric intravital microscopy," Optica 5, 1104-1112 (2018).
- Linking brain vascular physiology to hemodynamic response in ultra-high field MRI. Uludağ K, Blinder P. Neuroimage. 2018 Mar;168:279-295. doi: 10.1016/j.neuroimage.2017.02.063. Epub 2017 Feb 22. PMID: 28254456
- The cortical angiome: an interconnected vascular network with noncolumnar patterns of blood flow. Blinder P, Tsai PS, Kaufhold JP, Knutsen PM, Suhl H, Kleinfeld D. Nat Neurosci. 2013 Jul;16(7):889-97. doi: 10.1038/nn.3426. Epub 2013 Jun 9. PMID: 23749145
