Dr. Avner Thaler
Research work
The Laboratory for Early Markers of Neurodegeneration studies neural compensation and breakdown among patients with Parkinson's disease and subjects at risk for future disease applying multidisciplinary methods which include genetics, clinical, imaging and advanced statistical analyses.
Areas of interest & scientific knowledge
Cognitive Neuroscience
Specialization
Methodology
Human StudiesSelected Publications
- Omer N, Giladi N, Gurevich T, Bar-Shira A, Gana-Weisz M, Goldstein O, Kestenbaum M, Cedarbaum JM, Orr-Urtreger A, Mirelman A, Thaler A. A Possible Modifying Effect of the G2019S Mutation in the LRRK2 Gene on GBA Parkinson's Disease Mov Disord. 2020 Apr 30. doi: 10.1002/mds.28066. Online ahead of print.
- Jacob Y, Rosenberg-Katz K, Gurevich T, Helmich RC, Bloem BR, Orr-Urtreger A, Giladi N, Mirelman A, Hendler T, Thaler A. Network abnormalities among non-manifesting Parkinson disease related LRRK2 mutation carriers. Hum Brain Mapp. 2019 Jun 1;40(8):2546-2555.
- Thaler A, Bregman N, Gurevich T, Shiner T, Dror Y, Zmira O, Gan-Or Z, Bar-Shira A, Gana-Weisz M, Orr-Urtreger A, Giladi N, Mirelman A. Parkinson's disease phenotype is influenced by the severity of the mutations in the GBA gene. Parkinsonism Relat Disord. 2018 May 17
- Helmich RC*, Thaler A*, van Nuenen BF, Gurevich T, Mirelman A, Marder KS, Bressman S, Orr-Urtreger A, Giladi N, Bloem BR, Toni I; On behalf of the LRRK2 Ashkenazi Jewish Consortium. Reorganization of corticostriatal circuits in healthy G2019S LRRK2 carriers. Neurology. 2015 Jan 27;84(4):399-406.
- Thaler A, Kozlovski T, Gurevich T, Bar-Shira A, Gana-Weisz M, Orr-Urtreger A, Giladi N, Mirelman A. Survival rates among Parkinson's disease patients who carry mutations in the LRRK2 and GBA genes. Mov Disord. 2018 Oct;33(10):1656-1660
