Prof. Anat Mirelman

The research in the Laboratory of Early Markers Of Neurodegeneration (LEMON) aims to identify measures from multi-domains that can detect the development of neurodegeneration. We assess genetic, biological, imaging, clinical and digital measures obtained from healthy adults, those with known diseases and those with risk for developing disease. The main project in the lab is "The Genetics in Parkinson's disease Project" a longitudinal project evaluating patients and family members with genetic mutations associated with PD.  As part of this project we also explore neural prodromal changes using MRI, fMRI, EEG and fNIRS and sleep changes collected in the home with wearable sensors with the aim of configuring a personal risk through multi sensitive and quantitative modalities. Complementing the aim of identifying markers of disease, we also study reserve capacity and resilience of brain function as mitigators for neurodegeneration.  
The lab is home to researchers from different backgrounds: clinical (MD's and health science), engineering and data scientists (Bio-medical, electrical, mathematics and statistics) and behavioral (neuropsychology and neuroscience). The lab is situated in Tel Aviv Medcial Center (Ichilov)

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